A recent article published in RefluxMD discusses the latest research into the adverse effects of Proton Pump Inhibitors (PPI’s). This adds to mounting evidence that PPIs increase the risk of pneumonia and Clostridium difficile infections. In the article, they describe how acid suppressive drugs are often used in intensive care patients who require mechanical ventilation to decrease the risk of gastrointestinal (GI) bleeding from stress-induced ulcers. A sample of these patients who were prescribed either PPI’s or less powerful H2 blockers were monitored for infections. The outcome – The patients given PPIs were more likely to have pneumonia, C. diff, and GI bleeding compared to patients given H2 blockers.
What has your experience been of these acid blocking drugs?
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